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Moreover, among the 2441 patients on digoxin at one or more follow-up visit 1389 rate control group; 1052 rhythm control , the median duration of therapy was 32 interquartile range iqr 16, 46 months.

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numerous drug interactions with ssri agents can also pose a problem for patients taking other agents that are highly protein-bound or metabolized through the cytochrome p-450 pathway, such as barbiturates, benzodiazepines, digoxin, warfarin, and theophylline.

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consequently, the role of digoxin in the treatment of heart failure remains secondary table 4 , despite renewed interest in its use.


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